منابع مشابه
HCA-vision: Automated neurite outgrowth analysis.
Automating the analysis of neurons in culture represents a key aspect of the search for neuroactive compounds. A number of commercial neurite analysis software packages tend to measure some basic features such as total neurite length and number of branching points. However, with only these measurements, some differences between neurite morphologies that are clear to a human observer cannot be i...
متن کاملAutomated analysis of neurite branching in cultured cortical neurons using HCA-Vision.
Manual neuron tracing is a very labor-intensive task. In the drug screening context, the sheer number of images to process means that this approach is unrealistic. Moreover, the lack of reproducibility, objectivity, and auditing capability of manual tracing is limiting even in the context of smaller studies. We have developed fast, sensitive, and reliable algorithms for the purpose of detecting...
متن کاملDeconstructing The Columbia/HCA Investigation
Every issue raised by the current investigation into the business practices of Columbia/HCA serves as a signpost for the progress and problems inherent in market-driven health care reform. Actions against Columbia/HCA by regulators reveal deeply rooted resistance to the profit-motivated reforms embodied in the company’s philosophy: the public’s reluctance to accept necessary reductions in exces...
متن کاملDeconstructing The Columbia/HCA Investigation
Every issue raised by the current investigation into the business practices of Columbia/HCA serves as a signpost for the progress and problems inherent in market-driven health care reform. Actions against Columbia/HCA by regulators reveal deeply rooted resistance to the profit-motivated reforms embodied in the company’s philosophy: the public’s reluctance to accept necessary reductions in exces...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 2010
ISSN: 1087-0571,1552-454X
DOI: 10.1177/1087057110382894